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第一部分 奋斗历程1

此生唯愿济众生——记北京大学神经生理学家韩济生院士3

1/4世纪的求索19

人生的转折和选择25

半个世纪的愉快回顾32

Acupuncture Research Is Part of My Life39

韩济生院士简历46

第二部分 学术贡献49

一、韩济生院士的学术成就与学术思想51

韩济生院士与针刺镇痛51

求索者的奉献——记著名神经科学家、中国科学院院士、北京大学教授韩济生59

神经生物学重点学科点的建立及教学改革72

创办北京神经科学学会75

二、韩济生院士的主要学术论文78

The Role of Some Neurotransmitters of Brain in Finger-acupuncture Analgesia78

The Role of Central 5-Hydroxytryptamine in Acupuncture Analgesia90

Acupuncture Tolerance and Morphine Tolerance in the Rat99

Acupuncture Tolerance in Rats:Anti-opiate Substrates Implicated100

The Role of Central 5-Hydroxytryptamine in Acupuncture Analgesia and Acupuncture Tolerance103

Oynorphin:Potent Analgesic Effect in Spinal Cord of the Rat105

Neurochemical Basis of acupuncture Analgesia108

Acupuncture Has an Analgesic Effect in Rabbits121

Dynorphin:Important Mediator for Electroacupuncture Analgesia in the Spinal Cord of the Rabbit126

Antibody Microinjection Technique as a Tool to Clarify the Role of Opioid Peptides in Acupuncture Analgesia132

High and Low Frequency Electroacupuncture Analgesia are Mediated by Different Opioid Peptides133

Letters to the Editor134

Dynorphin-A-（1-13） Antagonizes Morphine Analgesia in the Brain and Potentiates Morphine Analgesia in the Spinal Cord136

Is Cholecystokinin Octapeptide （CCK-8） a Candidate for Endogenous Antiopioid Substrates？143

Cholecystokinin Octapeptide（CCK-8） : Antagonism to Electroacupuncture Analgesia and a Possible Role in Electroacupuncture Tolerance146

A Mesolimbic Neuronal Loop of Analgesia: Ⅰ. Activation by Morphine of a Serotonergic Pathway From Periaqueductal Gray to Nucleus Accumbens156

Studies on the Mesolimbic Loop of Antinociception: Ⅱ A Serotonin-enkephalin Interaction in the Nucleus Accumbens162

A Mesolimbic Loop of Analgesia Ⅲ. A Neuronal Pathway from Nucleus Accumbens to Periaqueductal Grey169

Electroacupuncture:An Alternative to Antidepressants for Treating Affective Diseases？174

Modification by CCK-8 of the Binding ofμ-,δ-,and κ-Opioid Receptors183

Effect of Low- and High-frequency TENS on Met-enkephalin-Arg-Phe and Dynorphin a Immunoreactivity in Human Lumbar CSF188

Neurochemical Studies on the Mesolimbic Circuitry of Antinociception192

Comparison of the Antinociceptive Effects Induced by Electroacupuncture and Transcutaneous Electrical Nerve Stimulation in the Rat200

All Three Types of Opioid Receptors in the Spinal Cord Are Important for 2/15 Hz Electroacupuncture Analgesia209

Optimal Conditions for Eliciting Maximal Electroacupuncture Analgesia with Dense and-Disperse Mode Stimulation216

Mobilization of Specific Neuropeptides by Peripheral Stimulation of Identified Frequencies221

Modification of Opioid Receptors and Uncoupling of Receptors from G Proteins as Possible Mechanisms Underlying Suppression of Opioid Binding by Cholecystokinin Octapeptide227

Intermittent-Alternating Mode of Administering Electroacupuncture Stimulation Postpones the Development of Electroacupuncture Tolerance232

Suppression of Morphine Abstinence Syndrome by Body Electroacupuncture of Different Frequencies in Rats237

Transcutaneous Electrical Nerve Stimulation for Treatment of Spinal Spasticity242

Heroin Addicts Treated with Transcutaneous Electrical Nerve Stimulation of Identified Frequencies247

Molecular Events Underlying the Anti-Opioid Effect of Cholecystokinin Octapeptide （CCK-8） in the Central Nervous System249

Brain Substrates Activated by Electroacupuncture （EA） of Different Frequencies （ Ⅱ ）:Role of Fos/Jun Proteins in EA-Induced Transcription of Preproenkephalin and Preprodynorphin Genes254

Cholecystokinin Octapeptide Reverses the Inhibitory Effect Induced by Electroacupuncture on C-Fiber Evoked Discharges261

Physiology of Acupuncture:Review of Thirty Years of Research266

Acupuncture Anesthesia （AA） Versus Acupuncture-assisted Anesthesia （AAA）272

Acupuncture Research and Neuroscience Development274

Endomorphine-1 Mediates 2 Hz but not 100 Hz Electroacupuncture Analgesia in the Rat278

Suppression of Morphine Withdrawal by Electroacupuncture in Rats :Dynorphin and k-opioid Receptor Implicated282

Spinal Kappa-opioid System Plays an Important Role in Suppressing Morphine Withdrawal Syndrome in the Rat289

Peripheral Electric Stimulation Inhibits Morphine-induced Place Preference in Rats294

Opioid and Antiopioid Peptides:A Model of Yin-Yang Balance in Acupuncture Mechanisms of Pain Modulation299

Acupuncture:Neuropeptide Release Produced by Electrical Stimulation of Different Frequencies310

Relations Between Brain Network Activation and Analgesic Effect Induced by Low vs. High Frequency Electrical Acupoint Stimulation In Different Subjects:A Functional Magnetic Resonance Imaging Study318

Acupuncture and Endorphins330

Repeated Peripheral Electrical Stimulations Suppress Both Morphine-induced CPP and Reinstatement of Extinguished CPP in Rats:Accelerated Expression of PPE and PPD mRNA in NAc Implicated334

Acupuncture345

三、韩济生院士主编的学术著作和期刊366

四、韩济生院士的部分讲话和文章372

2008年世界疼痛日、中国镇痛周暨建立疼痛科新闻发布会发言372

我与疼痛学会和疼痛杂志375

我与《生理科学进展》379

“北医百年，有我五十”380

悼念吴襄老师382

悼念王志均老师384

追忆季钟朴老师386

高山仰止，景行行止——怀念季钟朴老师388

五、韩济生院士的学术年表391

韩济生院士的学术活动大事记391

韩济生院士所获奖项目录400

韩济生院士发表论文目录402

韩济生院士国际会议演讲记录440

第三部分 治学之道449

探索奋进 坚持创新451

大爱无言 治学有道——记韩济生名誉院长对老区医学事业发展的关怀与指导453

济生：探索和开发457

成人之长 去人之短 培养我成长461

桃李满天下——从本科生教学到研究生教学464

“进进出出”的人才战略，培养和稳定人才队伍467

从科研思路培养人才470

从本科生到神经科学工作者——我和我的导师韩济生院士473

一路走来——我何以加盟北京大学神经科学研究所477

我父亲的教育思想480

第四部分 大师风范485

无私无畏的敬业精神——兼谈韩济生院士的教育思想487

不经一师 不长一智491

庆华诞 忆当年493

韩先生教我做人，做学问495

祝您健康 祝您成功498

美好的回忆500

经历就是财富503

过去的经历 不尽的回忆505

教授轶事——中国科学院院士、神经生理学家韩济生教授二三事507

韩济生教授——良师益友，做人的榜样510

永不陌生的记忆512

忆与韩济生教授共事时的一二事514

“在科学的道路上”——写在韩济生教授从教45周年之际515

辛勤的园丁517

我与韩老师520

难忘的岁月522

出国后与韩老师的三次会面523

您好，韩老师！——写在韩先生七十寿辰之际526

难忘北医528

一件小事530

严谨的学风 高尚的品德——记跟随韩济生教授及其前前后后532

记韩先生1996年访问波特兰市535

记在韩老师身边学习的二三事539

韩老师的两句名言541

一篇作文543

团结与勤奋544

热血冰心总关情——记我的导师韩济生教授546

山花烂漫549

一位与时间赛跑的老人——记我的导师韩济生教授551

韩老师的“训”553

印象554

从相识到相知555

在红枫季节里的回忆558

积沙成山 集腋成裘561

良师益友563

韩济生教授国际联系二三事566

韩氏仪戒毒16年中的二三事568

第五部分 社会影响571

复旦大学上海医学院贺信577

大连医科大学贺信578

哈尔滨医科大学贺信579

淡泊明志，宁静致远——庆祝韩济生院士从事教学60周年580

博学笃志，大家风范——北医百年校庆之际贺韩济生院士执教北医五十年581

中国神经科学学会贺词582

中国和世界疼痛医学的一面旗手——记韩济生院士从教60周年583

北京济生疼痛医学基金会贺信584

恭贺韩济生院士从教60周年585

韩济生——中国疼痛医学的开创者586

我与韩济生588

欲济苍生应未晚590

北大医学部庆祝韩济生院士从教六十周年594

北医百年，有我五十——祝贺北京大学医学部成立一百周年庆祝韩济生院士595

从教六十周年贡献北医五十年庆典595

韩济生院士荣获香港张安德中医药国际贡献奖596

韩济生院士获美国针刺研究学会“针刺研究终身成就奖”598

第六部分 人生风采599

人生轨迹601

幸福生活602

学习创业603

研究发明605

国际交流607

珍贵合影612

重要时刻614